There have been many reports about radiotherapy(RT) effect(either preoperative or postoperative adjuvant use) in treatment of rectal adenocarcinoma.
And recent articles about lowering of locoregional recurrence got attention of colo-rectal surgeon or his(their)coworkers.
In a retrospective analysis of 53 cases, from 1984 to 1992, we analyzed retrospectively locoregional recurrence pattern in patients who received radical curative surgical procedure for rectal cancer plus X-ray irradiation pre-or postoperatively
as
an
adjuvant treatment formulary.
15 patients who were treated with radical curative surgical resection alone by 1 surgeon including Miles' op., low anterior resection or anterior resection with the results of 20% locoregional recurrence were a control group in comparison to
other
grouped people.
20 patients(who received preoperative irradiation followed by curative surgery without intermission) categorized as stage B1(8 cases), stage B2(5cases), stage C1(3 cases), stage C2(4 cases) but their accumulated 5-year survival rate was 80% in
stage B1,
67% in stage B2, 60% in stage C1. Only 10% of them received recorded as a tenant of locoregional recurrence.
25 patients who received curative surgery with postoperative irradiation were 6 cases of stage B1(all were disease free more than 5 years), 8 cases of stage B2(5 years accumulation survival rate was 80%), 2 cases of stage C1 and 9 cases of stage
C2
44%
of them recorded as locoregional recurrence group.
8 patients received so-called sandwich technique(preoperative irradiation plus surgery and followed postoperative irradiation) with keeping results of 33% locoregional recurrence pattern.
So far, we couldn't pick up significant difference in long-term disease free interval between control group and preoperative irradiation plus radical curative surgery group.
But, preoperative radiation therapy casts reducing effect to locoregional recurrence by 10%comparing with control group.
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